This is a dictionary manuscript edited and completed by certain Chinese individuals in Manila and Spanish Dominican missionaries in the first half of the 17th century. The dictionary contains 27000 words and phrases in 1000 pages with Spanish, Chinese characters, romanized Hokkien and Mandarin. The collection of words and phrases is presented in four different categories: words, idioms, short sentences, and proverbs. It is the most comprehensive extant Hokkien-Spanish dictionary in the world from the 17th century, and it reveals the great intercultural interaction process and achievement during the early modern period between Hokkien and Spanish people. It is therefore an important and precious asset of "Memory of the World" for mankind.